Development of New Medicines A History

Development of New Medicines A History AnnaMaria Roca As many diseases were able to be cured due to new medicines, new diseases are soaring such as AIDS. However, peoples lives have expanded all around the world due to so many studies that even included drugs. As strange as it sounds, medical drugs became the new thing to cure certain diseases such as tuberculosis. During the time of the 20th century, the medical advances increased in many areas. The advancement evolved in many areas in biology, chemistry, physiology, pharmacology, and technology. Due to the knowledge that brought to their understanding, diseases got new treatments and cures as more studies grew larger. â€Å"Toward the end of the 19th century the study of herbal, chemical, and mineral remedies (what was called material medica) was transformed into the laboratory science of pharmacology(Planetseed)†. Plant drugs such as opium were being analyized and examined. After a while, it was ready to be manufactured due to researchers becoming comfortable of their knowledge about the drugs. The pharmaceutical industry was marketing these products near the start of the 20th century. This is when aspirin was invented as the company Bayer used a systematic chemical named acetylsalicylic acid. Paul Ehrlich studied in pharmacology and created the first effective treatment for syphilis. He manufactured the arsenic-based compound Salvarsan in 1909. Ehrlich also created the word â€Å"chemotherapy† and due to that, formed the first antibiotic drug. Later on, a guy named Gerhard produced the first useful sulfa drug which is also an antibiotic. This was used to treat streptoccal, strep, and diseases, including meningitis. Even though viral diseases weren’t being cured by antibiotics, antiviral vaccines did. Smallpox and polio were important to the vaccines that cured them. Polio, which is mainly a disease of childhood, causes paralysis. Jonas Salk and Albert Sabin were two scientist that worke to develop a polio vaccine. However, two different versions of this vaccine were developled, which were brought into the world in the mid-1950s. Salk’s developed the vaccine that was used on the deadly virus, while Sabin’s was used on the live one. Both that were used resulted in success. Polio was mostly put to rest by the end of the 20th century. In the 1920s, Alexander Fleming studied mold samples and found something that could be very important in the medical field. Mold was growing on bacteria samples which killed them. He recognized the mold as penicillin. During World War II, they used this with their extended research on injured soldiers to test it out the new drug. It proved very effective against anthrax, tetanus, and syphilis. This was also the first drug that worked against pneumonia. â€Å"Antiretroviral drugs were developed in the 1980s to combat AIDS. (Retroviruses are a class of virus.) Viruses mutate so quickly, however, that developing antiviral (and antiretroviral) agents has proved very difficult (Planetseed)†. So due to this, the multiple studies and hard work to develop a vaccine for malaria and AIDS are unsuccessful. Other antiviral vaccines were also developed to cure measles, chickenpox, and influenza. Vaccines against human papillomavirus and shingles became available in 2006. The first antiviral drug in the 1970’s were acyclovir that helped against some forms of herpes. However, this doesn’t cure herpes but its useful for not breaking out in herpe sores or blisters. Researchers have used many different approaches to develop drugs for patients. One major revolution in treating illnesses was a new understanding of theimmune system. The advancement in immunology has brought progress to all of the autoimmune diseases. The autoimmune diseases include type 1 diabetes, lupus, muscular dystrophy, and rheumatoid arthritis.the research has led to the development of immunotherapy. That would the use of drugs to modify the immune system. As immunosuppressive drugs help treat autoimmune diseases, it also is a great success in the area of organ transplantation. First transplant to occur where the kidneys and then soon later become the first heart transplants. However, those patients didn’t survive that long due to their body’s immune system rejecting the new organs. Cyclosporins was then created as the first effective immunosuppressive drug to fix that problem. This advanced even further for todays modern surgery that allows any organ of the human body to be transplanted from one individual to another. AIDS brought the science of immunology to new studies. AIDS was considered a death sentence since it destroy s the immune system as it resists infection. However, antiretroviral drug treatments extends the lives of individuals for years who are infected for many years, but it still doesn’t have a real cure. Studies in the immunological medical search also dealt with genetics. The body’s cells and organisms that could infect it were studied. They then understood the roles of genes, the chromosomes and cell metabolism. Deocyribonuclei acid, also known as DNA is located at the core of the chromosome. After the study of the body’s cells, the biggest breakthrough then happened. A biochemist Frank Crick, and biologist James Watson were able to interpret the structure of DNA and were then able to use it in medicine. They found out that many diseases can be drawn to genes or defective chromosomes. Due to these findings, it is now possible to be tested for diseases like cystic fibrosis, huntingtyons chorea and forms of breast cancer. Genetic engineering even allows us to generate new drugs such as insulin, interferon, human growth hormone, and other hormones used to stimulate blood cell production. Physicist Wilhelm Conrad Roentgen discovered X-rays and made it capable to look at the internal organs of the body. This resulted in easier diagnoses for broken bones, cancer, and other diseases. Later on a physiologist, invented the first electrocardiograph. This was used for people with heart problems which the device was used to record electrical activity of the heart muscles. Tubes were then used to drain fluids or used to put in medicine were put into the heart and liver. The technologies that were discovered were ultrasound imaging, computerized tomography scans, positron emission tomography scans and magnetic resonance imaging. X-rays are a form of radiation which you would consider very dangerous to the body. After a while Radiologists realized that x rays were a form of radiation and are very dangerous to the body which resulted in them now using the lowest doses possible. They also became more knowledgeable about the use of X-rays to destroy unwanted cells. Radiation has become a treatment for cancer. Technology also helps people who need surgery. It allows the surgeon to look into further of the body which also allows radical invasive surgeries. Flexible endoscopes also became useful for hernias, gall bladders, kidneys, and knees. It is based on a fiber optic technology which is used for a keyhole surgery. It is a scope that has a laser which can cut like a sharp knife which makes a tiny incision. During the mid 20th century, a heart-lung machine was manufactured. It keeps patients alive by maintaining blood circulation while a surgeon is operating on an unbeating heart. Artificial organs are also a development that became useful for many individuals. Due to the fact that there aren’t enough organs for people, artificial organs help them to survive until one is found for them. Hemodialysis which was developed by a scientist named Willem Kolff. It helps patients live longer with kidney failure. Missing limbs were also being helped due to the development of prosthetics. Artificial limbs use to be made of metal and wood which later on turned into plastic that was developed in the mid-20th century. â€Å"But now, advanced materials, such as carbon fiber, high-tech plastics and metals, have enabled researchers to create devices that operate by electronic attachment to the muscles(Planetseed)†. In otherwords, Individuals lives have expanded all around the world due to so many studies of different things. The medical advancement evolved in many areas in biology, chemistry, physiology, pharmacology, and technology. Due to the knowledge that brought to their understanding like the medical drugs becoming a factor of helping people. As the studies grow, the more treamtns and cure grow because that is the key factor to it all. Studying and learning and eventually achieving what you’ve been working hard for doesn’t only help yourself but other lives as well. WORKS CITED: 20th Century Medical Advances | History of Medicine | PlanetSEED. 20th Century Medical Advances | History of Medicine | PlanetSEED. Web. 18 May 2015. Parker, Steve. Medical Advances. Austin, Tex.: Raintree Steck-Vaughn, 1998. Print. Fong, Kevin. Extreme Medicine: How Exploration Transformed Medicine in the Twentieth Century. 2014. Print.

Prosecution Of Macbeth (if He Was Tried For The Murder Of Duncan) :: essays research papers

Ladies and Gentlemen of the jury, we have heard the defence glorify Macbeth in an effort to cloud the horrible acts of murder that he committed. The question that we are here to answer today stands, ?is Macbeth guilty of the murder of our beloved king, Duncan?. Many questions cloud our judgement today. Did Macbeth have a motive to kill the king? Did Macbeth meticulously premeditate the murder of Duncan? Did Macbeth carryout, then cover up the murder of King Duncan? Ladies and gentlemen it will be difficult, nay impossible for you to deny any of these allegations of murder against Macbeth, because simply put, he did commit these vicious acts of murder. Members of the jury, King Duncan was ruler of Scotland in a kingdom which the Scottish lineage to the throne moves from father to first-born son. However a member from within the same bloodline could lay claim to the throne if Duncan had no living sons. Therefore a question ponders in your mind. Why would Macbeth murder king Duncan? Macbeth had no legitimate claim to the throne However ladies and gentleman, what some of you may not know is that Macbeth was in-fact the King?s cousin. Before Duncan?s untimely death he stated to Macbeth: ?O valiant cousin! Worthy gentleman? (pg 32) which confirms that Macbeth was in-fact Duncan?s cousin. Therefore Macbeth was in the same bloodline as Duncan, and therefore could take the throne if Duncan had no sons who were able to ascend to the throne. But since Duncan had already named Malcolm as heir to the throne, Duncan had to be murdered. This was always in the back of MacBeth?s mind from the very beginning. The prophecy of the three witches, only fired his imagination to confirm the terrible deeds he was already planning, the death of king Duncan and tearing the throne from his dying hands. Macbeth stated ?I am settled, and bend up each corporal agent to this terrible feat. Away, and mock the time with fairest show: False face must hide what false heart doth know.? (Pg 55) This demonstrates that he was resolute and determined to use all the powers of his body to commit that terrible murder. He was to deceive the world by framing two innocent servants and appearing distraught by Duncan?s untimely death. The death of a king, who was a kind-hearted man, was aided by the blatant mis-use of his own love, loyalty and trust for his closest friends

Silence Kills, Animal Farm Essay

Haley Zrnchik Mrs. Hawkins Honors English 1, Red 1 13 December 2012 Silence Kills In George Orwell’s Animal Farm, Benjamin, a soft-spoken donkey, finds his once peaceful home transformed into a tyrannical dictatorship led by a power-hungry pig named Napoleon. Because of Benjamin’s reserved nature, he ultimately was able to lead Animal Farm into its oppression. Benjamin’s silence, his ability to follow without question, and his inability to share his wisdom with the other animals turned him into one of the main contributors to the tyrannical behavior that occurred and the loss of freedom and equality on Animal Farm.When someone keeps their thoughts silent, it usually allows wrong to happen; in this case, Benjamin and his reserved nature is what helped to fuel the farm’s oppression. So when: â€Å"Benjamin . . . seemed to understand, but would say nothing† (109) he allowed the other animals to go without knowing about Napoleon’s true intentions . Perhaps Benjamin assumed that his silence would protect him, and that by staying silent, he was not creating more drama and instead helping to minimize it. Even though Benjamin is one of the more intelligent animals on the farm, his standoffishness is what helped Napoleon lead as a dictator: â€Å"Benjamin . . nodded his muzzle with a knowing air† (109) Benjamin had the ability to share his wisdom with the other animals on the farm. However, instead of spreading the truth about Napoleon, Benjamin kept to himself and refused to meddle in what he considered to be â€Å"nonsense†. Benjamin refused to voice his thoughts and because of that, he allowed his friends to die, his home to be destroyed, and his life to be turned into that of a follower. Instead of speaking up, Benjamin quietly followed the orders he was given. So while he never volunteered to do extra work, he never did less than what he was supposed to: â€Å". . . ven . . . Benjamin . . . did [his] shareâ₠¬  (60-61) Because Benjamin did not try to overthrow Napoleon, he allowed Napoleon to become a stronger and more influential dictator on Animal Farm. Had Benjamin not allowed himself to be turned into a follower, he most likely would have been able to prevent the farm’s oppression. More often than not, it is the followers that help to fuel a tyranny: â€Å"Benjamin was watching . . . [silently and] intently† (102). Followers sit, watch, do what they are told, and they listen. While Benjamin may not have agreed with Napoleon’s rulings, he never objected to any of them either.Benjamin is a follower and he always will be, because even though he possesses the qualities of a leader, he doesn’t have the strength, the care, or the willpower to speak up. Benjamin was always quiet soul, but when he lost Boxer, the pain in his heart only intensified. Benjamin tried to save his dear friend before he was sent to the â€Å"knacker’s† but alas, he wasnâ €™t fast enough: â€Å"Come at once! They’re taking Boxer away! † he shouted . . . Sure enough, there was a . . . van, drawn by two horses . . . And Boxer’s stall was empty . . . â€Å"Good-bye, Boxer! † [The animals] chorused . . . â€Å"Fools! Fools! † shouted Benjamin . . . â€Å"Fools!Do you not see what is written on . . . that van? . . . Alfred Simmonds, Horse Slaughterer . . . They are taking Boxer to the knacker’s! † . . . But the van was already . . . drawing away from them . . . [And] Boxer was never seen again. After losing Boxer, Benjamin recoiled deeper into his shell of silence. Little did Benjamin realize that if he chose to harness his anger and use it as a tool to fight against Napoleon, he probably would have been victorious. Even though he spoke in a condescending and undermining tone before, after Boxer died, Benjamin chose not to speak at all: â€Å"Only old Benjamin was much the same as ever . . except . . . since Boxer’s death, more morose and taciturn than ever† (128) Benjamin’s growing silence caused him to become a bigger contributor to the loss of freedom and equality on Animal Farm. At this point, he wouldn’t speak up; Benjamin confirmed his spot as a follower and never as anything more. Sometimes silence is the deadliest weapon. Benjamin proved that by remaining quiet through a time of oppression, one would only be helping to promote a leader’s totalitarianism.His stubborn silence, his adamancy towards following his orders, and his taciturn attitude after the death of Boxer only stood to show that a follower sometimes can be the strongest contribution to a tyranny. Napoleon’s dictatorship, while strong, would not have been as successful had it not been for his followers. Benjamin and the others, while they may not have realized it, were key attributes needed to lead to the ultimate removal of freedom and equality on Animal Farm. Works Cit ed Orwell, George. Animal Farm: With Connections. Austin, TX: Holt, Rinehart, and Winston, 1999. Print.

Police Officers And Officers Police And Corrections Officers

If My Mind Could Forget the Things My Eyes Have Seen Abuse by police officers and officers in penal institutions is a big subject in the media now. Turn to a news station and the chances of seeing at least on case are pretty high. The most unreported incidents, however, is actually assault on police officers and corrections officers. The media does not report these issues nearly as much as it tries to portray officer assault on criminals. Why is it that the media covers up the big issue of officer assault and reports the â€Å"innocent† criminals being assaulted? When the media is trying to scare someone they don’t say criminals are bad, instead, make it seem like the selfless officers risking their lives are the bad guys and use it as a scare tactic to create distrust and panic in the public. Abuse falls under six definitions when applied to law enforcement. Physical abuse: The blatant beating, striking, or physical mistreatment of an inmate. This is a very vague area because any physical contact with an inmate can be reported as abuse. Psychological abuse: The mental degradation of an inmate through embarrassment, unnecessary command or criticism. Unlawful interrogation, which is literally unheard of anymore, means the use of starvation, sleep deprivation, dehydration, etc. Excessive force: When compliance must be obtained physically and the amount of force used far exceeds the need. 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